The Freemasons Foundation Centre for Men’s Health is proud to announce that one of our valued members, Associate Professor Lisa Butler from the Adelaide Prostate Cancer Research Centre, Dame Roma Mitchell Cancer Research Laboratories, has been awarded a prestigious Future Fellowship from the Australian Research Council. Lisa is also a member of the Centre’s Management Group.
Through its funding, the Future Fellowship program promotes research in areas of critical national importance by giving outstanding researchers incentives to conduct their research in Australia. The aim of Future Fellowships is to attract and retain the best and brightest mid-career researchers. This funding for five years will allow Lisa and her research team to pursue, with vigor, her important translational research in the area of prostate cancer treatment.
What is her project? There is a critical need in oncology drug development for better biomarkers of response to prostate cancer therapies, clinically to assist with treatment decision making, and pre-clinically to facilitate translation of emerging drug agents into clinical practice. Using a unique explant culture model, this project will identify protein and lipid markers that can be used to accurately and reliably assess response to androgen receptor (AR)-targeting therapies in human prostate tumours. The identification and functional assessment of these biomarkers will identify those that can be used as surrogate endpoints in clinical trials so non-responsive men can be taken off ineffective drugs earlier to reduce side effects, facilitate earlier regulatory approval of new drugs and lead to improved options for the management of prostate cancer.
The Australian Research Council funds programs and supports researchers across all fields of science and less so in health science which makes Lisa’s achievement even more impressive. In fact, only 3 Future Fellowships for cancer research were awarded nationally.