US National Institutes of Health: Advancing HIV Therapeutic Vaccine Science (U01 Clinical Trial Required)

This opportunity uses the U01 Research Project – Cooperative Agreements funding mechanism.

This announcement solicits applications that will advance understanding of vaccine regimens and immune responses that sustainably suppress virus in HIV-infected individuals.

Funding will be made available to support small, multi-arm, comparative clinical trials designed to identify correlations between levels of induced immune response and HIV virologic control.

Vaccines may be combined with adjuvants and/or other modifiers of the immune response to HIV.

Funding & Duration

The scope of the proposed project should determine the project period. The maximum project period is 5 years.


Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Submission Requirements & Due Dates

Further Information

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