US National Institutes of Health BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

This opportunity uses the R01 Research Project Grant funding mechanism.

A total of 11 participating institutes and centres of the National Institutes of Health invite applications for their BRAIN initiative – development and validation of novel tools to probe cell-specific and circuit-specific processes in the brain (R01 clinical trial not allowed) funding opportunity.

This award supports the development and validation of novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform or exploit cell-type or circuit-level specificity.

The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Additionally, tools that can be used in a number of species or model organisms rather than those restricted to a single species are highly desired as well as applications that provide approaches that break through existing technical barriers to substantially improve current capabilities.

Funding & Duration

Application budgets are not limited but need to reflect the actual needs of the proposed project.

The maximum project period is 3 years.


Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Submission Requirements & Due Dates

Further Information

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