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US NIH National Institute on Aging: Analyses of Adherence Strategies and Data Sets from CALERIE to Explore Behavioral and Psychosocial Aspects of Sustained Caloric Restriction in Humans (R01 Clinical Trial Not Allowed)

This opportunity uses the R01 Research Project Grant funding mechanism.

Funding Opportunity Announcement (FOA) Number: PA-18-825

Applications are invited for research projects (R01) involving secondary analyses of data in the Computerized Tracking System (CTS) database from the CALERIE (Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy) trial, to explore behavioural and psychosocial aspects of sustained caloric restriction (CR) in humans, including the translation of the CR adherence strategies used in the trial to promote healthy behaviors, especially for the prevention of weight gain with age.

CALERIE was the first trial in humans to specifically focus on the effects of sustained CR. It demonstrated feasibility of sustained human CR (for at least two years) and favorable effects on predictors of longevity, as well as on cardiometabolic risk factors. The sustained weight loss in CALERIE has not been previously attained in any clinical study in non-obese individuals.

Companion Schemes

  • PA-18-826 – R21 Exploratory/Developmental Grant

Funding & Duration

The number of awards is contingent on NIH appropriations and the submission of a sufficient number of meritorious applications.

Application budgets are not limited but must reflect the actual need of the proposed project. Projects may last up to five years.

Eligibility

Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Submission Requirements & Due Dates

Further Information

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