US NIH National Institute on Aging: Analyses of CALERIE Data and Biospecimens to Elucidate Mechanisms of Caloric Restriction (CR)-Induced Effects in Humans (R01 Clinical Trial Not Allowed)

This opportunity uses the R01 Research Project Grant funding mechanism.

Funding Opportunity Announcement (FOA) Number: PA-18-823

Applications are invited for research projects (R01) involving secondary analyses of data and/or stored biospecimens from the CALERIE (Comprehensive Assessment of Long- term Effects of Reducing Intake of Energy) trial.

The goal of this funding opportunity announcement (FOA) is to encourage analyses that will lead to a more detailed understanding of the effects of caloric restriction (CR) on risk factors for chronic diseases, as well as, the cellular/molecular mechanisms mediating the effects of sustained CR in humans.

Companion Schemes

  • PA-18-824 , R21 Exploratory/Developmental Grant

Funding & Duration

The number of awards is contingent on NIH appropriations and the submission of a sufficient number of meritorious applications.

Application budgets are not limited but must reflect the actual need of the proposed project. Projects may last up to five years.


Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Submission Requirements & Due Date

Further Information

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