US NIH National Cancer Institute: Physical Activity and Weight Control Interventions Among Cancer Survivors: Effects on Biomarkers of Prognosis and Survival (R01 Clinical Trial Optional)

The National Cancer Institute invites applications for its physical activity and weight control interventions among cancer survivors – effects on biomarkers of prognosis and survival (R01 clinical trial optional) funding opportunity. This encourages transdisciplinary and translational research that will identify the specific biological or biobehavioural pathways through which physical activity or weight control may affect cancer prognosis and survival.

Research should test the effects of physical activity, alone or in combination with weight control, on biomarkers of cancer prognosis among cancer survivors identified by previous animal or observational research on established biomarkers other than insulin or glucose metabolism, especially those obtained from tumour tissue sourced from repeat biopsies where available.

Applications should use experimental designs, such as randomised controlled clinical trials, fractional factorial designs, and include transdisciplinary approaches that bring together behavioural intervention expertise, cancer biology, and other basic and clinical science disciplines relevant to the pathways being studied.

This opportunity uses the R01 Research Project Grant funding mechanism.

Funding & Duration

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is five years.


US and foreign for-profit and non-profit organisations and public and private organisations may apply.

Companion Funding Opportunity

  • PAR-18-892, R21 Exploratory/Developmental Grant

Submission Requirements & Due Date

Further Information

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