National Institutes of Health (NIH): Notices of Special Interest

The National Institutes of Health (NIH) has released the below Notices of Special Interest (NOSI):

National Cancer Institute (NCI)

This Notice was released to inform potential applicants to NCI grants of special interest to promote research that incorporates biological information within population-based cancer epidemiologic studies to identify and understand how the interplay between environmental exposures (e.g. chemical and physical exposures, dietary, and other exposures) and germline genetic variation contribute to cancer risk. Biological information can include functional annotations of the genome (e.g. methylation, promoters or enhancers); methods of linking variants to genes (e.g. expression quantitative trait loci analysis), gene pathway or network-based approaches (e.g. network modeling); analysis of metabolites or biomarkers, or data from mechanistic studies.

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

This Notice is intended to stimulate research to address critical gaps in our understanding of iodine nutrition, assessment, and status-related outcomes (with an emphasis on mild-to-moderate dietary insufficiency).

Iodine is an essential nutrient that must be obtained via the food supply in order to meet established requirements for health. Despite a long and evolving history of understanding with regard to the impact of iodine deficiency, meeting iodine requirements remains a domestic and global challenge. Because of its key role in human development, adequate iodine nutrition of women of reproductive age, during pregnancy, and infancy is a critical public health priority. Despite significant progress in terms of public health programs and interventions, significant gaps remain to be filled in order to fully inform these efforts, particularly with regard to our understanding of the biology, assessment, and outcomes of iodine status in these vulnerable groups.

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