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Congratulations to Dr Phillip Tully, NHMRC Translating Research Into Practice (TRIP) Fellow, on being awarded a Vanguard grant from the Heart Foundation.

Patients with cardiovascular disease and comorbid depression are a group traditionally characterised by high healthcare usage, chronic disease morbidity, and premature death. Collaborative care is standard evidence-based practice in the USA and UK for coronary heart disease and heart failure patients with comorbid depression, however, this model of healthcare is uncommon in Australia. Consequently, the pragmatic aspects of implementing collaborative depression care in Australian cardiovascular settings remains largely unknown.

This study is designed as a quality improvement initiative to improve current depression identification practices in coronary heart disease populations, while utilising implementation-science principles to improve the uptake of evidence based collaborative depression care. The study is set across cardiology services in 4 public hospitals in metropolitan Adelaide, and each hospital or cluster crosses over to the intervention in sequential steps determined by randomisation. By increasing the skills and resources required to implement collaborative depression care, it is anticipated that the study will improve clinical care practices for identifying and treating depression in coronary heart disease patients. For patients, the study intervention seeks to improve patient depression symptoms and quality of life.

The study Chief Investigators include Professor John Beltrame (The University of Adelaide and The Queen Elizabeth Hospital), Professor Derek Chew (Flinders University and Flinders Medical Centre), and Professor Alex Brown (South Australian Health and Medical Research Institute and The University of Adelaide). Associate investigators and collaborators include Professor Gary Wittert, Professor Deborah Turnbull, and Associate Professor Andrew Vincent (Freemasons Foundation Centre for Men’s Health, The University of Adelaide), Associate Professor Billingsley Kaambwa and Professor Robyn Clark (Flinders University), Dr. Rosanna Tavella (The Queen Elizabeth Hospital), and Associate Professor Carolyn Astley (SAHMRI, Health Translation SA).

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We are very pleased to welcome Mr Terry Hall to the FFCMH men’s health research volunteer team.  Terry is a University of Adelaide alumni and retired staff member.

Terry worked as a Senior IT Training Officer, in the Technology & Digital Enablement Group of the University’s Information Technology & Digital Services for 15 years.  He retired earlier this year. Terry has expertise in data systems specialising in Access and Excel.

Here is a snapshot of Terry
– Married with 2 daughters and an 2 and 2/3 grandchildren
– A Pétanque player – travelling the world playing in tournaments
– A rugby player and fan – so for all World Cup updates speak to Terry
– A men’s health and healthy lifestyle advocate – His local gym in NextGen

Terry volunteers for the Centre on Thursdays and is based on Level 6 of the AHMS Building.  He is currently working with Dr Sean Martin to map the Florey Adelaide Male Ageing Study data across from Access into the new data management system being used across the Centre – RedCap.  Terry is rapidly becoming an expert in RedCap so please contact the Centre is you have any data systems support.

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Reported in the journal Oncogene in 2013, Professor Lisa Butler (pictured left) and collaborators, including the Centre’s Professor Wayne Tilley and senior author, Professor Karen Knudsen from the Kimmel Cancer Center, Thomas Jefferson University in USA. inhibition of the cyclin/cyclin-dependent kinase/retinoblastoma (CDK4/6) pathway that is critical for cell replication may have a role in controlling some human cancers where this pathway is amplified. Using the human prostate cancer explant model developed in the Dame Roma Mitchell Cancer Research Laboratories. The CDK4/6 inhibitor impaired the capacity of prostate cancer cells in human prostate tumours to proliferate and that this could be achieved independent of concurrent treatment with hormone-based therapy and radiotherapy.
Professor Butler now leads the Prostate Cancer Research Group at SAHMRI which focuses on therapeutics and lipids in prostate cancer.  Nearly five years later and with funding from Cancer Australia, Professor Butler and with medical oncologist Professor Lisa Horvath from the Chris O’Brien Lifehouse in NSW, are now testing the safety and potential effect of the same CDK4/6 inhibitor (ribociclib) in an early phase clinical trial in men undergoing surgery for high risk, localised prostate cancer. THese CDK4/6 inhibitors are already being used to treat women with breast cancer.
For the study, men receive 400mg of oral ribociclib daily for 21 days prior to prostate surgery.  Markers of cancer cell proliferation will be Biopsies of the prostate cancer prior to treatment and then at the time of prostatectomy will be compared for . Men are being evaluated for safety signals to ensure the drug is safe to proceed to larger studies,
It is hoped this research will help demonstrate the activity of this drug against prostate cancers, and lay the groundwork for more trials.
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The Hon Tony Piccolo MP (Member for Light) has been a passionate and committed member of the Board of Patrons of the Freemasons Foundation Centre for Men’s Health since the Centre’s inception.  Tony recently spoke about the Centre and the organisations in his community working to advance men’s health and wellbeing at the SA Men’s […]

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The Centre congratulates Dr Kootsy Canuto, Post-Doctoral Research Fellow in the Wardliparingga Aboriginal Research Unit at SAHMRI, on being awarding an Emerging Leadership Investigator Grant in the recently announced National Health and Medical Research Council funding announcements.  His 5 year award of $650,750 is titled “Enough talk, time for action: Developing, implementing and evaluating co-designed […]

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Dr Phillip Tully is a Psychologist and a post-doctoral Research Fellow in the FFCMH leading the Vascular and Brain Health research group. He is funded by a TRIP (translating research into practice) Fellowship from the Commonwealth Government’s National Health and Medical Research Council. Phillip’s clinical and research interests focus on two of the three leading causes of disease burden […]

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The 8th National Men’s Shed Gathering will be held at the Morphettville Racecourse Adelaide, SA and is expected to attract over 300 delegates. It aims to promote the Community of Men’s Sheds throughout Australia and the contribution Men’s Sheds make to their own communities. Delegates will come from a broad spectrum of backgrounds, including ‘shedders’, shed coordinators, […]

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The Centre congratulates A/Professor John Litt AM on being appointed as Member of the Order of Australia (AM) for his significant service to preventive medicine as an influenza specialist. We have been privileged to have John as a member of the Centre’s Scientific Advisory Committee since its inception in 2007.  He is recognised for his expertise in […]

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Movember continues to support advances in the care of men with prostate cancer through the award of a research grant to Centre members Dr Michael O’Callaghan from the South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC, Prostate Cancer Registry), Dr Andrew Vincent and the Investigator team. The research will involve using data collected by the South […]

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On June 13, during Men’s Health Week, the Centre hosted the Australian Men’s Health Forum’s SA Men’s Health Awards at which the SA Men’s Health Report card was released and community organisations across South Australia working to advance the health and well-being of men and boys were acknowledged and celebrated.  A number of these organisations […]

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